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VincristineVincristine is a chemotherapeutic agent that has become popular especially for Kaposiform Hemangioendotheliomas and Hemangiomatosis with liver involvement. It is given through a central line weekly. This drug has been part of several pediatric chemotherapeutic regimens and appears to have far fewer side effects than steroids. Its use was popularized for the treatment of children who were having difficulty weaning off steroids as well as for children whose hemangiomas were resistant to steroid treatment.